New Publication from the Interest Group 2019
A new International Study by the PALB2 Interest Group was published this week, which can be found here A short video by Dr Marc Tischkowitz summarising the Study can be …
The PALB2 Interest Group – An Update, 2019
We would like to thank again all the participating families who have contributed their clinical details to the PALB2 study over the years as without your help and support our …
Men – affected by breast cancer and PALB2 mutations
Recent publication: Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene Most associate breast cancer and women but breast …
Spotlight on….Dr Marc Tischkowitz
‘Research is an ongoing process, we are always improving our knowledge and making new discoveries’ Marc Tischkowitz is a University Reader and Honorary Consultant in the Department of Medical Genetics …
What is a Variant of Unknown Significance?
Variant of Unknown Significance As the number of genes available for sequencing is increasing, we are finding more and more genetic variants of unknown significance, which are hard to interpret. …
We appreciate your support!
We are very grateful to all of you who have contacted us in recent months and for wishing to participate in our PALB2 study. Thank you for getting in touch …
Please help us to learn more about PALB2 gene
If you have a confirmed PALB2 mutation or/and others in your family have been found to have a PALB2 mutation, please contact us. By participating in our study you will …
What is PALB2 gene?
PALB2 – partner and localizer of BRCA2 The PALB2 gene protects us from breast cancer unless this gene is altered (mutated). It contains instructions to make a protein that works …
Implications of having PALB2 mutation
If you have a PALB2 mutation this means that you are at increased risk of breast cancer and your doctor may recommend increased surveillance using the combination of breast MRI and/or …